MONTH IN REVIEW | January 2024

We’re looking forward to lots of exciting things in 2024!

Happy New Year! We’re excited to share another year with you through our monthly e-newsletters! We hope that you had a lovely holiday season and a happy start ot 2024.

Congratulations!

We would like to say congratulations to Dr. Alexander Baumgartner who was offered and accepter the NeuroNEXT Fellowship Research Grant. He received a competitive one-year grant from the University of Colorado Rocky Mountain NeuroNEXT for his pilot study. You can read more about Dr. Baumgartner’s research interests here.

Dr. Isabelle Buard, Dr. Matthew Woodward, Dr. Jeanne Feuerstein, and Ying Liu presented posters at the 2023 Parkinson’s Study Group in December 2023.

Welcome, Dr. Aslam!

The Movement Disorders Faculty and staff are excited to welcome Sana Aslam, DO.

She is a board-certified neurologist who specializes in Movement Disorders at the University of Colorado Anschutz Medical Campus. She completed her undergraduate education at Wellesley College and Medical School at Lake Erie College of Osteopathic Medicine. Following medical school, she completed her Neurology training and a Movement Disorders and Deep Brain Stimulation Fellowship at the Barrow Neurological Institute.

Read more about Dr. Aslam on our Meet the Team! page.

Upcoming Events

Parkinson’s Foundation Revolution Ride

Saturday, February 24, 2024, 12:30 PM
Parkinson’s Foundation
CycleBar Southwest Plaza
Come see us that the Parkinson’s Foundation fundraiser. We’ll be cheering on riders and giving out some goodies!
Learn more here.

From Dependent to Independent: Treatment Options for Essential Tremor

This series of talks will resume again in March. Please stay tuned for details.

In the News

Here are a few noteworthy articles that were published recently. Some of our faculty have contributed to the articles below. We encourage you to check them out!

Research

The MDC Faculty regularly publish articles in peer-reviewed journals. Some of these may not be available to read without a subscription. But, these listings will let you know what the faculty have been working on lately!

  • Cristini J, Potvin-Desrochers A, Seo F, Dagher A, Postuma RB, Rosa-Neto P, Carrier J, Amara AW, Steib S, Paquette C, Roig M. The Effect of Different Types of Exercise on Sleep Quality and Architecture in Parkinson Disease: A Single-Blinded Randomized Clinical Trial Protocol. Phys Ther. 2024 Jan 1;104(1):pzad073. doi: 10.1093/ptj/pzad073. PMID: 37354450; PMCID: PMC10776310.

Have you considered participating in clinical research?

Did you know…

  • all of the current therapies we have came from clinical trials?
  • people in clinical trials tend to have better clinical outcomes? (This could be because they are more closely observed by a expert clinician, the placebo effect, or because it inspires hope.)
  • the Movement Disorders Center has interventional and observational trials? This means we have studies that offer therapies for movement disorders and we have studies where clinicians monitor the progress of diseases with no therapy offered.

If you are interested in learning more, reach out to our research recruitment team at NeuroResearch@cuanschutz.edu or 303-724-4644.

2023 World Parkinson Disease Day

April 11 is World Parkinson Disease Day. The faculty and staff at the University of Colorado are proud to work with the Parkinson Community. While patient care is a large part of our care for the Parkinson’s community, there is a lot more they do outside of the clinic.

The Anschutz Medical Campus is a training facility for upcoming medical providers. Our faculty participates in the education of young medical students and residents. Additionally, we have a movement disorders fellowship program to train the next generation of movement disorders neurologists. In addition to becoming part of our own faculty, these trainees have gone on to serve movement disorders communities in underserved areas and continue clinical research in their own practices. You can learn more about our program and its importance by visitng our Fund-a-Fellow page.

Our faculty are also leading research to find new therapies or better understand Parkinson disease. This research can include trials of potential new medications or devices. It also includes research projects initiated by our own faculty that help patients and care partners. If you are interested in learning more about our research, we have a research catalog and a research website for you to view. If you are interested in participating in clinical research, contact our research recruitment team. Many resources are available in English and Spanish.
e-mail: NeuroResearch@cuanschutz.edu
phone: 303-724-4644
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In 2022, our faculty provided 64 formal talks to patients, care partners, medical providers, and medical learners. These talks were regional, national, and international. Our faculty finds so much value in providing access to updated information to the Parkinson’s community to help them take control of their health. If you are interested in having someone speak to your group, please reach out to movement@ucdenver.edu.

In addition, we will host our 10th Annual Parkinson Disease Symposium on October 28, 2023. Follow our Facebook page for updated details. You can look for an event page on our website soon. We look forward to an informational and exciting day with many special extras this year.

The University of Colorado Movement Disorders Center looks forward to continuing these missions in 2023 and beyond. We look forward to connecting with you.

Transitions

The Movement Disorders Center is growing again! A handful of providers have moved on from our center for various personal reasons, including retirement and spouses being transferred to new positions. But we are excited to welcome new faculty to our group.

The faculty and staff at the center continue to be dedicated to improving the lives of people with movement disorders.

We announced in our newsletter that Dr. Alex Baumgartner and Dr. Michael Korsmo will be graduating from our fellowship program and will be joining us as faculty in August. Both bring niched areas of expertise that will help round out our center.

Dr. Baumgartner will be joining Dr. Kern as part of our advanced therapies and deep brain stimulation (DBS) team in the operating room. In the past few years, the number of DBS surgeries performed yearly has nearly doubled. The team has recently added a new neurosurgeon and more programmers as well. Dr. Baumgartner will see patients in the clinic at the Anschutz Medical Campus and in Lone Tree.

Dr. Korsmo will be expanding our reach to underserved communities. In addition, he will be seeing patients at our main clinic on the Anschutz Medical Campus and at our Boulder clinic.

Dr. Vaughan is expanding her neuro-palliative clinic. Her clinic will now be found at the Anschutz Medical Campus. By moving her clinic, Dr. Vaughan and her patients will have access to more services and resources. Her focus will now be neuro-palliative care; the main difference is that she will not be the primary movement disorders specialist for patients. She will still serve the movement disorders community through neuro-palliative care during all stages of diseases. She will still be available to all patients for neuro-palliative care via telehealth.

For more information about neuro-palliative care, you can read our Fall 2021 newsletter.

MDC Receives Parkinson’s Foundation Award

The University of Colorado Movement Disorders Center received an award from the Parkinson’s Foundation for the Highest Team Participation for the Parkinson’s Foundation Palliative Care Education Course. The award was presented at this year’s COE Leadership Conference and was accepted by Ryan Khan, a chaplain who works closely with our Palliative Care team.

In 2020, the Parkinson’s Foundation launched an initiative to make palliative care a standard practice of care across all Centers of Excellence in the United States. The MDC received the award for being the Center of Excellence (COE) with the most team members who have completed the online Palliative Care Training.

The Movement Disorders Center is honored to receive this award in recognition to our dedication to patient care.

Dr. Forbes Accepted to Clinical Faculty Scholars Program

Congratulations to Dr. Emily Forbes on her acceptance into the Colorado Clinical and Translational Sciences Institute’s (CCTSI) Clinical Faculty Scholars Program (CFSP). This program enrolls up to five junior faculty members each year. The program helps young researchers obtain grant funding for their career growth or their first independent investigator-initiated project. Often these are K-awards or R-awards which are funded by the NIH. These can also be awards from large non-profit organizations. The CCTSI trains these budding researchers through guided project development, educational seminars, grant writing classes, and mentorship participation.

Dr. Forbes’s project will build a Neurogenetics database. The first goal will be to characterize genetic causes of Parkinson’s disease in the University of Colorado’s patient population. She will follow this group over time to see how they respond to treatment based on their genetic variant. She will build this database to include phenotypic (observable characteristics) and genotypic (genetic characteristics) information across different specialties in Neurology. This will lead to a department resource for genetics research. Her long-term aim is to develop a tool to advance fair and the best genetic testing for patients. This will also help to provide thorough genetic counseling. This tool will make clinical trials for disease-modifying treatments available to more patients and quicken the rate of developing new therapies. Additionally, it will widen the availability of clinical trials to patient populations.

Other Movement faculty alumni of the CFSP program include Dr. Michelle Fullard and Dr. Samantha Holden and former movement disorders faculty, Dr. Brian Berman, and Dr. Benzi Kluger.

Being part of a medical school means that in addition to seeing patients, our faculty are also involved in additional pursuits. One of these pursuits is conducting clinical research related to their field. Most research falls into two categories: clinical trials and investigator-initiated research. Clinical trials are a type of clinical research that aims to determine the safety and effectiveness of the medication, devices, and treatment regimens. Investigator-initiated research starts with new ideas that the researcher comes up with themself. The researcher then is responsible for creating a trial to test their idea and then carrying out the trial. All research must adhere to strict rules and regulations. You can read more about the research here.

Research Update | The Relationship Between Olfactory Dysfunction and Constipation in Early Parkinson’s Disease

Written by Alex Baumgartner, MD

In a recent issue of the journal Movement Disorders, colleagues and I published a study examining the relationship between two of the most common ‘non-motor’ symptoms of Parkinson’s disease (PD): decreased sense of smell (olfactory dysfunction) and constipation. It has been known for some time that these symptoms often start several years or even decades before the typical ‘motor’ symptoms of PD, which include tremor, stiffness, and slow movement. Going along with this, accumulation of the abnormal protein alpha-synuclein, which is thought to play a critical role in the development of PD, have been found in the nasal passages and GI tracts of PD patients before it is found in the brain. This has led many to hypothesize that PD may actually begin in the nose or in the gut and spread from there to the brain.

We wanted to explore whether we could find evidence that for some people, PD begins in the nasal passages while in other people, it begins in the gut. We hypothesized that if people had PD originating in the nasal passages only, they would have only loss of smell and not constipation. On the other hand, if PD originated in the GI tract only, they would have constipation but not loss of smell. We looked at data from the Parkinson’s Progression Markers Initiative (PPMI), which collects information from patients who have recently been diagnosed with PD.

movement disorders specialist colorado

We found that at the time people are diagnosed with PD, they tend to have problems with smelling and constipation to similar degrees. That is, people with worse sense of smell also tend to have worse constipation, and those with minimal loss of smell tend to have mild constipation. This finding actually went against our hypothesis. There may be a few reasons for this. The first is that the time of diagnosis of PD (based on tremor, slowness, and stiffness) may be too late to detect a difference in smell and constipation. Even if PD begins in either the nose or the gut, symptoms in the other location may have already ‘caught up’ with the first. The second possible explanation is that PD may begin in both locations at about the same time. This is called the dual-hit hypothesis, and has gained popularity in recent years. In the future, we hope to expand our research to help elucidate where and when the earliest signs of Parkinson’s occur.

Board Certification

Congratulations to our two first-year fellows, Alex Baumgartner, MD and Michael Korsmo, MD, for passing their neurology board examinations through the American Board of Psychiatry and Neurology!

When we select fellows for our training program, they must be eligible to take these board examinations. This means they must meet all of the minimum requirements to take the exam by the start of their fellowship training. Fellows typically take the test towards the end of their first semester which is the earliest the test is offered.

Board certifications are important because they promote and assess the competence of physicians when beginning and throughout their careers. Board-certified physicians must provide proof that they are continuing their education through Continuing Medical Education credits and are recertified at set intervals throughout their career.

While board certifications are not required to practice medicine, they are an extra step many physicians choose to take. The certifications demonstrate the physicians are keeping up with the most recent advancements in their specialties and their desire to provide high-quality care to their patients. Board certifications are specific to each specialty and therefore maintain more specific standards to maintain certifcation.

All of the movement disorders specialists at the University of Colorado Movement Disorders Center are board-certified in neurology.

Say congratulations to our fellows if you see them in clinic!